Medical Urethral System for Erection (MUSE)

MUSE ® (Medical Urethral System for Erection ) is a single-use, medicated transurethral system  to deliver the drug  to the male urethra. Alprostadil is suspended in polyethylene glycol 1450 (as excipient) and is formed into a medicated pellet (micro-suppository measuring 1.4 mm in diameter by 3 mm or 6 mm in length) that resides in the tip of a translucent hollow applicator. MUSE is administered by inserting the applicator stem into the urethra after urination. The pellet containing alprostadil is delivered by depressing the applicator button  The components of the delivery system are constructed of medical grade polypropylene. Each MUSE system is packaged in an individual foil pouch. MUSE is available in 4 dosage strengths: 125 mcg, 250 mcg, 500 mcg, and 1000 mcg.